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ACM ByteCast is a podcast series from ACM’s Practitioners Board in which hosts Rashmi Mohan, Bruke Kifle, Scott Hanselman, Sabrina Hsueh, and Harald Störrle interview researchers, practitioners, and innovators who are at the intersection of computing research and practice. In each episode, guests will share their experiences, the lessons they’ve learned, and their own visions for the future of computing.
Episodes

Thursday May 29, 2025
Kate Kallot - Episode 70
Thursday May 29, 2025
Thursday May 29, 2025
In this episode of ACM ByteCast, our special guest host Scott Hanselman (of The Hanselminutes Podcast) welcomes Kate Kallot, founder and CEO of Amini, an impact-driven AI company based in Nairobi, which focuses on the critical issue of data scarcity in Africa and its implications for AI development. Before Amini, her career spanned leadership positions at global tech companies, including NVIDIA, where she led global developer relations and expansion into emerging markets, and Arm, where she was a pivotal figure in the Tiny Machine Learning (TinyML) movement. At Intel, she led the development of the world’s first AI development kit in a USB form factor, the Neural Compute Stick, bringing computer vision and Al to IoT and edge devices to millions for the first time. Kate is a recognized expert and influencer in the AI field, advising international organizations and governments on the potential and challenges of AI for good. Her work has been recognized by TIME’s 100 Most Influential People in AI, the World Economic Forum as a Tech Pioneer, and One Young World as Entrepreneur of the Year 2024. A trusted voice in global AI policy and digital equity, Kate serves as Vice Chair of the ICC Global Environmental and Energy Commission and is a member of EY’s Global AI Advisory Council.
In the interview, Kate explains the barriers to AI adoption in Africa, stemming from challenges with digital and environmental data infrastructure. She shares her work collecting and validating data in key areas such as climate and agriculture through state-of-the-art technologies and partnerships with private companies, using a bottom-up approach. Kate and Scott also talk about Amini’s commitment to open source and community collaboration in areas such as geospatial data science, and the global applications of Amini’s work in Africa to other geographies with similar characteristics.
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Tuesday May 13, 2025
Michael J. Freedman - Episode 69
Tuesday May 13, 2025
Tuesday May 13, 2025
In this episode of ACM ByteCast, Rashmi Mohan hosts ACM Fellow Michael J. Freedman, Robert E. Kahn Professor of Computer Science at Princeton University and co-Founder and CTO of Timescale. Michael’s research interests are in distributed systems, networking, and security. Over the course of his student and professional career, he designed and operated the Coral Content Distribution Network, a peer-to-peer content distribution network; co-founded (with Martin Casado) Illuminics Systems, an IP analytics company; and designed TimescaleDB and JetStream. His many honors and recognitions include the 2018 ACM Grace Murray Hopper Award, Presidential Early Career Award for Scientists and Engineers, and SIGOPS Mark Weiser Award.
Michael shares what drew him to computer science, highlighting the value of initiative and gumption as an undergraduate student, and how he became interested in security and privacy, working on peer-to-peer systems before cloud computing became ubiquitous. He discusses his work on Coral CDN during his PhD research, applying research outcomes to build scalable systems and learning to harness customer feedback good user experience. Michael also talks extensively about Timescale, one of the fastest databases for real-time analytics, or time series data, and explains the roles of CTO and head engineer at a technology company.

Thursday Apr 17, 2025
Peter Lee - Episode 68
Thursday Apr 17, 2025
Thursday Apr 17, 2025
In this episode of ACM ByteCast, our special guest host Scott Hanselman (of The Hanselminutes Podcast) welcomes ACM Fellow Peter Lee, President of Microsoft Research. As leader of Microsoft Research, Peter incubates new research-powered products and lines of business in areas such as AI, computing foundations, health, and life sciences. Before Microsoft, he established a new technology office that created operational capabilities in ML, data science, and computational social science at DARPA, and before that he was head of the CS department at CMU. Peter served on President Obama’s Commission on Enhancing National Cybersecurity and has testified before both the US House Science and Technology Committee and the US Senate Commerce Committee. He coauthored the bestselling book The AI Revolution in Medicine: GPT-4 and Beyond. In 2024, he was named by Time magazine as one of the 100 most influential people in health and life sciences.
In the interview, Peter reflects on his 40+ years in computer science, from working on PDP-11s and Commodore Amigas to modern AI advancements. He highlights how modern technologies, built on decades of research, have become indispensable. He also talks about his healthcare journey, including work that earned him election to the National Academy of Medicine, and the potential (and limitations) of AI in medicine. Peter and Scott touch on the impact of LLMs, the lack of ethics education in traditional CS curricula, the challenges posed by growing AI complexity. Peter also highlights some important Microsoft Research work in AI for Science and Quantum Computing.

Thursday Apr 03, 2025
Mary Lou Jepsen - Episode 67
Thursday Apr 03, 2025
Thursday Apr 03, 2025
In this episode of ACM ByteCast, our special guest host Scott Hanselman (of The Hanselminutes Podcast) welcomes Mary Lou Jepsen, CEO and Founder of Openwater, a technical executive and inventor in the fields of display, imaging, and computer hardware with about 300 patents published or issued to her name. She founded and led two moonshots at Google X and was later an executive at Facebook/Oculus VR. Prior to this, she was a professor at the MIT Media Lab, where she co-founded and was the first CTO of One Laptop per Child (OLPC), and later founded Pixel Qi in Taipei, Taiwan, focused on the design and manufacture of displays. Jepsen has been named as one of the 100 most influential people in the world by Time Magazine (“Time 100”), CNN’s top “10 thinkers” in science and technology and has won numerous awards numerous from professional societies in the fields of optics, display, and electronics. She’s a frequent keynote speaker, has given two highly viewed TED talks, and is frequently featured in top global press publications.
Mary Lou discusses her work with Openwater, a startup working on innovative imaging technology using infrared light, ultrasound, and electromagnetics to diagnose and potentially treat diseases, and aims to leapfrog traditional drug development. She and Scott talk about the role of patents in manufacturing, and regulatory and technological barriers in healthcare innovation. They also dive into the advantages of the company’s open-source model, both for its software and hardware designs. Mary Lou highlights some of their breakthroughs, including stroke detection and non-invasive cancer treatment. She also talks about reducing cost and scaling production, next steps in clinical trials, and future possibilities with open source.

Wednesday Mar 19, 2025
Travis S. Humble - Episode 66
Wednesday Mar 19, 2025
Wednesday Mar 19, 2025
In this episode of ACM ByteCast, Rashmi Mohan hosts Travis S. Humble, Director of the Quantum Science Center (QSC), a Distinguished Scientist at Oak Ridge National Laboratory, and Director of the lab’s Quantum Computing Institute. He leads the development of new quantum technologies and infrastructure to impact the DOE mission of scientific discovery through quantum computing. As director of the QSC, Travis leads the innovation of scalable, resilient quantum information technologies through new materials, devices, and algorithms and facilitates the transfer of quantum technologies to the broadest audience. He also holds a joint faculty appointment with the University of Tennessee Bredesen Center for Interdisciplinary Research and Graduate Education working with students on energy-efficient computing solutions. Travis is Editor-in-Chief for ACM Transactions on Quantum Computing, Associate Editor for Quantum Information Processing, and Co-Chair of the IEEE Quantum Initiative.
Travis describes his journey into quantum computing, which began in theoretical chemistry, where he studied quantum processes in chemical reactions. He explains the difference between classical and quantum computing and why quantum computing is particularly well suited for scientific applications such as drug discovery and energy solutions. He talks about Oak Ridge’s quantum computing resources and how researchers can access them. Travis also stresses the role education in advancing quantum computing and shares his predictions for its near future.

Monday Mar 03, 2025
Darja Smite - Episode 65
Monday Mar 03, 2025
Monday Mar 03, 2025
In this episode of ACM ByteCast, Harald Störrle hosts Darja Smite, Professor of Software Engineering at Blekinge Institute of Technology and a part-time research scientist at SINTEF ICT. Darja is an expert on the future of work and the impact of globalization and offshoring in software companies. She has conducted research with and international companies such as ABB, Boss Media, CALVI, DXC, Emerson Process Management, Ericsson, SONY, Spotify, and, Telenor and has insights from cooperating with offshore vendors in India, China, Poland, Latvia, Ukraine and Russia.
Darja shares her background, growing up in Latvia with a love for math, and later moving to Sweden for work and Norway to conduct research at SINTEF, one of Europe's largest independent research organizations. She shares some of her research findings on outsourcing and discusses the effect automation will have on outsourcing and profitability. She also discusses reasons why people stay or leave their jobs, as well as cultural differences and the challenge of people from different cultures finding common ground. Darja also touches on the impact of COVID on work practices in the past five years and offers advice for people considering a career in IT.

Tuesday Feb 18, 2025
Chieko Asakawa - Episode 64
Tuesday Feb 18, 2025
Tuesday Feb 18, 2025
In this episode, part of a special collaboration between ACM ByteCast and the American Medical Informatics Association (AMIA)’s For Your Informatics podcast, Sabrina Hsueh hosts accessibility researcher and inventor Chieko Asakawa, an IBM Fellow at the IBM T.J. Watson Research Center, the Chief Executive Director of The National Museum of Emerging Science and Innovation (Miraikan) in Japan, and an IBM Distinguished Service Professor at Carnegie Mellon University. Chieko’s inventions include the Home Page Reader (HPR); a word processor for Braille documents; a digital library for Braille documents; an application to improve accessibility of streaming services; and, most recently, the AI Suitcase project. Her career has been recognized with numerous prestigious awards and honors, including becoming the first Japanese woman IBM Fellow in 2009, receiving the “Medal of Honor with Purple Ribbon” from the Emperor of Japan in 2013, her induction into the US National Inventors Hall of Fame in 2019, being named a Fellow of the National Academy of Inventors, and the ACM SIGACCESS Award for Outstanding Contributions to Computing and Accessibility in 2024.
In the interview, Chieko shares how becoming blind early in life led her to work in accessibility research. She talks about her IBM team’s work on the Home Page Reader, the first practical voice browser to provide effective internet access for blind and visually impaired computer users, as well as more recent work on the AI suitcase, a robot that helps visually impaired people walk around and navigate independently. Chieko and Sabrina touch on AI’s potential in aiding accessibility and the inspiration for the AI Suitcase. She offers advice and best practices for both early and mid-career researchers and interdisciplinary professionals.

Thursday Jan 30, 2025
Alvin Wang Graylin - Episode 63
Thursday Jan 30, 2025
Thursday Jan 30, 2025
In this episode of ACM ByteCast, Rashmi Mohan hosts Alvin Wang Graylin, Global VP of Corporate Development at HTC. Alvin is also Chairman of the Virtual World Society, Vice-Chair of the Industry of VR Alliance, and President of the Virtual Reality Venture Capital Alliance. Alvin is a leader in the virtual and augmented reality industries. As a serial entrepreneur, he founded four venture-backed startups across sectors including AI-driven conversational search, mobile social networks, ad tech, and big data AI analytics, spanning both China and the U.S. As an active investor, he funded more than 100 startups and played a pivotal role in the establishment of HTC’s ViveX Global VR accelerator and SOSV’s mobile internet investment incubator. A frequent keynote speaker at leading international conferences, Alvin is regularly featured in major media outlets, where he provides thought leadership on immersive computing (AR/VR/MR), AI, entrepreneurship, venture investing, and the Chinese market. His latest book, Our Next Reality, examines how AI and XR convergence will reshape society. He holds an M.S. in CS specializing in AI from MIT, an M.S. in Business from MIT’s Sloan School of Management, and a B.S. in Electrical Engineering from the University of Washington, focusing on VR, AI, and CPU architecture.
Alvin describes his early introduction to technology and computers after immigrating to the U.S. from China and later working at the first VR-focused research lab outside the military at the University of Washington. He highlights some of his pioneering contributions to the consumer PC, mobile, and internet industries in China, including helping establish Intel’s China office. Alvin explains how his background in NLP and AI helped him navigate and address the complexities of Chinese as a language for mobile search and shares some milestones from his work in China, at companies he founded and later at HTC. He touches on the early challenges and limitations of VR, progress made, and its exciting future promise. He also discusses some major advancements in XR technology, its transformative potential for education, and explains the synergy between AI and XR and the need for positive adoption at this pivotal moment in technological history.

Tuesday Jan 14, 2025
Jennifer Chayes - Episode 62
Tuesday Jan 14, 2025
Tuesday Jan 14, 2025
In this episode of ACM ByteCast, Bruke Kifle hosts ACM Fellow and ACM Distinguished Service Award recipient Jennifer Chayes, Dean of the College of Computing, Data Science, and Society at UC Berkeley. Before joining Berkeley, she co-founded the Theory Group at Microsoft Research Redmond and later founded and led three interdisciplinary labs: Microsoft Research New England, New York City, and Montreal. Her research areas include phase transitions in CS, structural and dynamical properties of networks including graph algorithms, and applications of ML. Jennifer is one of the inventors of the field of graphons, widely used for the ML of large-scale networks. Her recent work includes generative AI and ML theory in areas like cancer, immunotherapy, climate change, and ethical decision making, with more than 150 scientific papers authored and 30 patents she co-invented. Her honors and recognitions include the Anita Borg Institute Women of Vision Leadership Award, SIAM’s John von Neumann Lecture Award (the highest honor bestowed by SIAM), and election to the American Academy of Arts and Sciences and the National Academy of Sciences. She serves on numerous boards and advisory committees and has served on the ACM A.M. Turing Award Selection Committee.
Jennifer shares her early experience as the child of Iranian immigrants, dropping out of high school and learning to embrace risk. She describes her journey from being a pre-med biology major to a PhD in mathematical physics, and how her love of theory and an interest in interdisciplinary work led her to start a Theory Group at Microsoft Research. She also relates how her later interest in economics and game theory led to the founding of Microsoft Research New England, and highlights some of her work there. She and Bruke talk about the challenges she has navigated throughout her career, and how that has influenced her approach to interdisciplinary research. Jennifer also shares her vision and goals for the College of Computing, Data Science, and Society at UC Berkeley. Finally, she opines on the skills needed for future leaders in computing, some of the urgent problems of our time, and offers some advice to young computing professionals.

Tuesday Dec 17, 2024
Roger Dannenberg - Episode 61
Tuesday Dec 17, 2024
Tuesday Dec 17, 2024
In this episode of ACM ByteCast, Bruke Kifle hosts ACM Fellow Roger Dannenberg, a Professor Emeritus of Computer Science, Art & Music at Carnegie Mellon University. Dannenberg is internationally renowned for his research in computer music, particularly in the areas of programming language design, real-time interactive systems, and AI music. Throughout his career, he has developed innovative technologies that have revolutionized the music industry and is known for creating Audacity, the widely known and used audio editor. In addition to his academic work, His other projects include Music Prodigy, aiming to help thousands of beginning musicians and Proxor, aiming to help software developers launch a successful career. Roger is also an accomplished musician and composer, having performed in prestigious venues around the world.
Roger traces his two lifelong passions for computer science and music, and his fascination with the connection between sound, mathematics, and physics. He describes the signal changes in interactive computer music, which once required specialized hardware but has since been replaced by ubiquitous software-based audio processing. Roger and Bruke discuss the promise of AI in music, especially for enhancing creativity and live performance, as well as the challenges of balancing AI with human labor and creativity. Roger also describes his work on the powerful open-source audio editor Audacity (co-developed with former student Dominic Mazzoni), which has democratized music production and is now used by millions of users worldwide. Finally, he talks about some recent projects in music analysis and composition, and reflects on his role as an academic and advisor.